Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.49 |
| ▸ | MMP12 | P39900 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 4/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243340 | 0.90 | EPHX1 (0.44) | MMP13MMP12MMP8ALDH1A1EPHX1 | |
| SCHEMBL6276800 | 0.77 | MMP13 (0.49) | MMP13MMP12MMP8MEN1ALDH1A1 | |
| SCHEMBL6271220 | 0.74 | MMP13 (0.57) | MMP13MMP12MMP8MEN1ALDH1A1 | |
| SCHEMBL6802716 | 0.74 | MMP13 (0.57) | MMP13MMP12MMP8MEN1ALDH1A1 | |
| SCHEMBL3244251 | 0.73 | HPGD (0.54) | MMP13MMP8ALDH1A1KMT2AMMP1 | |
| SCHEMBL25432674 | 0.71 | ALDH1A1 (0.47) | MMP13MMP8ALDH1A1MMP3MMP1 | |
| SCHEMBL3158459 | 0.71 | RAB9A (0.49) | MEN1ALDH1A1KMT2A | |
| SCHEMBL8600793 | 0.71 | MMP12 (0.64) | MMP13MMP12MMP8FDFT1FFAR1 | |
| SCHEMBL21234184 | 0.71 | HPGD (0.51) | MMP13MMP8ALDH1A1KMT2AMMP1 | |
| SCHEMBL7829131 | 0.71 | MMP12 (0.59) | MMP13MMP12MMP8FDFT1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073599-A2 | INHIBITORS OF HEPATITIS C VIRUS, COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |