Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320315 | 0.90 | PRCP (0.37) | HSD11B1PRCPLMNATDP1HCRTR1 | |
| SCHEMBL8323729 | 0.90 | PRCP (0.35) | HSD11B1PRCPHTTRAB9ATDP1 | |
| SCHEMBL8324904 | 0.89 | HRH3 (0.40) | PRCPNPC1 | |
| SCHEMBL8325063 | 0.89 | HRH4 (0.38) | PRCPNPC1RAB9ATDP1 | |
| SCHEMBL8325059 | 0.88 | LMNA (0.36) | HPGDPRCPTP53ALDH1A1LMNA | |
| SCHEMBL8321623 | 0.87 | GPBAR1 (0.40) | PRCPSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8318144 | 0.86 | KMT2A (0.35) | KCNK3PRCPMAPTALDH1A1TSHR | |
| SCHEMBL8321663 | 0.86 | HSD11B1 (0.32) | HSD11B1PRCPALDH1A1 | |
| SCHEMBL8324593 | 0.85 | HSD11B1 (0.32) | HSD11B1PRCP | |
| SCHEMBL8324137 | 0.85 | PRCP (0.33) | PRCPTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058743-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | disclosed |