Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | MET | P08581 | 6/20 | 0.37 |
| ▸ | PRCP | P42785 | 3/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320315 | 0.93 | PRCP (0.37) | HRH3PRCP | |
| SCHEMBL8323729 | 0.93 | PRCP (0.35) | PRCP | |
| SCHEMBL8318975 | 0.89 | HPGD (0.39) | PRCPNPC1 | |
| SCHEMBL8321663 | 0.86 | HSD11B1 (0.32) | PRCP | |
| SCHEMBL8325059 | 0.86 | LMNA (0.36) | PRCP | |
| SCHEMBL8324593 | 0.86 | HSD11B1 (0.32) | PRCP | |
| SCHEMBL8318144 | 0.86 | KMT2A (0.35) | PRCP | |
| SCHEMBL8325063 | 0.86 | HRH4 (0.38) | HRH3PRCPNPC1 | |
| SCHEMBL8321623 | 0.84 | GPBAR1 (0.40) | PRCP | |
| SCHEMBL8324137 | 0.82 | PRCP (0.33) | HRH3PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058743-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | disclosed |