Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320315 | 0.96 | PRCP (0.37) | PRCPFABP4HSD11B1SLC22A12TDP1 | |
| SCHEMBL8324904 | 0.93 | HRH3 (0.40) | PRCP | |
| SCHEMBL8318975 | 0.90 | HPGD (0.39) | PRCPRAB9AHSD11B1HTTTDP1 | |
| SCHEMBL8325059 | 0.89 | LMNA (0.36) | PRCPHTTTDP1HCRTR1HCRTR2 | |
| SCHEMBL8318144 | 0.88 | KMT2A (0.35) | PRCPRAB9AKDM4EHCRTR1HCRTR2 | |
| SCHEMBL8321663 | 0.88 | HSD11B1 (0.32) | PRCPHSD11B1 | |
| SCHEMBL8324593 | 0.87 | HSD11B1 (0.32) | PRCPHSD11B1 | |
| SCHEMBL8325063 | 0.86 | HRH4 (0.38) | PRCPRAB9ATDP1 | |
| SCHEMBL8324137 | 0.84 | PRCP (0.33) | PRCPTDP1 | |
| SCHEMBL8321623 | 0.84 | GPBAR1 (0.40) | PRCPKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058743-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | disclosed |