Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319636 | 0.83 | MAOB (0.36) | MAOBHCRTR1HCRTR2MAOAMAPT | |
| SCHEMBL8322076 | 0.83 | HCRTR1 (0.36) | MAOBHCRTR1HCRTR2MAPTKDM4E | |
| SCHEMBL8324080 | 0.81 | TUBB4A (0.35) | ADORA2AMAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL8321836 | 0.80 | EDNRA (0.37) | MAOBMEN1KMT2A | |
| SCHEMBL8801256 | 0.76 | HCRTR1 (0.35) | HCRTR1HCRTR2ADORA2A | |
| SCHEMBL8918214 | 0.74 | CES2 (0.36) | HCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL8319649 | 0.71 | MAOB (0.39) | MAOBHCRTR1HCRTR2MAOATMIGD3 | |
| SCHEMBL8323374 | 0.69 | EDNRA (0.37) | MAOAMAPTMEN1NPC1RAB9A | |
| SCHEMBL8572771 | 0.66 | EDNRB (0.34) | — | |
| SCHEMBL8321570 | 0.66 | NPC1 (0.35) | MAOBHCRTR1HCRTR2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752424-B1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5877120-A | Nicotinic acid derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0752424-A1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-01-08 | — | — | EP | disclosed |