Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.35 |
| ▸ | TUBB | P07437 | 4/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322076 | 0.85 | HCRTR1 (0.36) | CES2ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8324489 | 0.82 | KDM4E (0.34) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8321836 | 0.82 | EDNRA (0.37) | CES2MEN1KMT2ATHRB | |
| SCHEMBL8319030 | 0.81 | MAOB (0.38) | POLQADORA2AKDM4EMAPTHSD17B10 | |
| SCHEMBL8801256 | 0.77 | HCRTR1 (0.35) | CES2ADORA2A | |
| SCHEMBL8918214 | 0.75 | CES2 (0.36) | CES2LMNASMN1; SMN2 | |
| SCHEMBL8323374 | 0.71 | EDNRA (0.37) | CES2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8572771 | 0.68 | EDNRB (0.34) | — | |
| SCHEMBL8321570 | 0.67 | NPC1 (0.35) | CES2ALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL8810384 | 0.67 | NPSR1 (0.36) | LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752424-B1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5877120-A | Nicotinic acid derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0752424-A1 | NICOTINIC ACID DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-01-08 | — | — | EP | disclosed |