Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 9/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335871 | 0.84 | HRH3 (0.66) | POLBHRH3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16980536 | 0.82 | POLB (0.59) | POLBHRH3L3MBTL1RAB9ANPC1 | |
| SCHEMBL16980401 | 0.81 | RAB9A (0.53) | POLBHRH3L3MBTL1RAB9ANPC1 | |
| SCHEMBL8314076 | 0.79 | SSTR3 (0.61) | POLBSSTR3HRH3RAB9ANPC1 | |
| SCHEMBL19329149 | 0.79 | POLB (0.70) | CCR2POLBSSTR3HRH3RAB9A | |
| SCHEMBL20063373 | 0.76 | KDM1A (0.47) | SSTR3L3MBTL1 | |
| SCHEMBL8315514 | 0.76 | SSTR3 (0.69) | POLBSSTR3HRH3RAB9AKMT2A | |
| SCHEMBL3899502 | 0.76 | KDM1A (0.56) | POLBSSTR3HRH3L3MBTL1 | |
| SCHEMBL3899511 | 0.76 | KDM1A (0.56) | POLBSSTR3HRH3L3MBTL1 | |
| SCHEMBL21361200 | 0.75 | HRH3 (0.49) | HRH3KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787716-B1 | Isoprene derivatives | NISSHIN FLOUR MILLING CO (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5756475-A | POLYISOPRENE MODIFIED WITH AMINE WITH ANTICANCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0787716-A1 | Isoprene derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |