Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322748 | 0.85 | ALDH1A1 (0.37) | ALDH1A1MAPTL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL31042134 | 0.84 | ATM (0.43) | ALDH1A1MAPTATMTDP1SNCA | |
| SCHEMBL8317675 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTATMTDP1SNCA | |
| SCHEMBL28575301 | 0.74 | ATM (0.41) | ALDH1A1MAPTATMTDP1SNCA | |
| SCHEMBL29676432 | 0.74 | ATM (0.41) | ALDH1A1MAPTATMTDP1SNCA | |
| SCHEMBL1028874 | 0.72 | PDGFRB (0.56) | ALDH1A1MAPTATMTDP1SNCA | |
| SCHEMBL31083656 | 0.71 | KMT2A (0.46) | ALDH1A1MAPTATMTDP1SNCA | |
| SCHEMBL25314269 | 0.70 | CHEK1 (0.47) | ALDH1A1MAPTATMTDP1SNCA | |
| SCHEMBL8876679 | 0.70 | ALDH1A1 (0.65) | ALDH1A1MAPTTDP1HTTL3MBTL1 | |
| SCHEMBL9687422 | 0.70 | TDP1 (0.51) | ALDH1A1MAPTATMTDP1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883282-A | UREA CHEMICAL INTERMEDIATES; RICE | AMERICAN CYANAMID COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5670641-A | 3-(3-aryloxyphenyl)-1-(substituted methyl)-S-triazine-2,4,6-oxo or thiotrione herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-09-23 | — | — | US | disclosed |