Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319186 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12768192 | 0.71 | PDGFRB (0.62) | ALDH1A1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL16537288 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL31042134 | 0.68 | ATM (0.43) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9770859 | 0.67 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL29679513 | 0.65 | SIRT6 (0.48) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL1640894 | 0.65 | SIRT6 (0.48) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL12933630 | 0.65 | HCAR3 (0.35) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL8320236 | 0.65 | MEN1 (0.46) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7976503 | 0.64 | PDGFRB (0.53) | ALDH1A1PDGFRBFGFR1PDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883282-A | UREA CHEMICAL INTERMEDIATES; RICE | AMERICAN CYANAMID COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5670641-A | 3-(3-aryloxyphenyl)-1-(substituted methyl)-S-triazine-2,4,6-oxo or thiotrione herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-09-23 | — | — | US | disclosed |