Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316701 | 0.91 | HCAR3 (0.40) | ALDH1A1L3MBTL1MAPTKDM4EHTT | |
| SCHEMBL8313561 | 0.87 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTKDM4ETDP1 | |
| SCHEMBL31042134 | 0.80 | ATM (0.43) | ALDH1A1L3MBTL1MAPTKDM4EATM | |
| SCHEMBL8319186 | 0.77 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPTATMTDP1 | |
| SCHEMBL10687975 | 0.71 | ATM (0.53) | ALDH1A1L3MBTL1MAPTKDM4EATM | |
| SCHEMBL29676432 | 0.71 | ATM (0.41) | ALDH1A1L3MBTL1MAPTATMTDP1 | |
| SCHEMBL28575301 | 0.71 | ATM (0.41) | ALDH1A1L3MBTL1MAPTATMTDP1 | |
| SCHEMBL1028874 | 0.69 | PDGFRB (0.56) | ALDH1A1L3MBTL1MAPTATMTDP1 | |
| SCHEMBL8263434 | 0.69 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EATMTDP1 | |
| SCHEMBL7745956 | 0.69 | LMNA (0.57) | ALDH1A1L3MBTL1MAPTATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| CN-1033327-C | Process for preparing tricyclotriazolo derivatives and their use | TORAY INDUSTRIES (JP) | 1996-11-20 | — | — | CN | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |