Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.56 |
| ▸ | CLPP | Q16740 | 12/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8327802 | 0.99 | SLC6A5 (0.55) | SLC6A5CLPPKDM4EALDH1A1ACHE | |
| SCHEMBL8323169 | 0.80 | ACHE (0.57) | SLC6A5KDM4EALDH1A1ACHEGABRA1 | |
| SCHEMBL8319661 | 0.79 | CLPP (0.54) | CLPPKDM4EALDH1A1ACHEHDAC10 | |
| Hydrochloric Acid SCHEMBL8323662 | 0.79 | ACHE (0.56) | SLC6A5ACHEGABRA1GABRA2 | |
| Hydrochloric Acid SCHEMBL8321634 | 0.78 | CLPP (0.53) | CLPPKDM4EALDH1A1ACHEHDAC10 | |
| SCHEMBL20495944 | 0.76 | HDAC6 (0.61) | HDAC10HDAC8HDAC6 | |
| SCHEMBL2625346 | 0.75 | SLC6A5 (0.80) | SLC6A5CLPPKDM4EALDH1A1ACHE | |
| SCHEMBL19667094 | 0.74 | SLC6A5 (0.56) | SLC6A5CLPPKDM4EALDH1A1ACHE | |
| SCHEMBL27224412 | 0.74 | SLC6A5 (0.62) | SLC6A5CLPPKDM4EALDH1A1ACHE | |
| SCHEMBL8324851 | 0.72 | ACHE (0.55) | SLC6A5KDM4EALDH1A1ACHEGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715162-B | Protein kinase modulators | 南京盖特医药技术有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-11091477-B2 | Protein kinase regulators | Madera Therapeutics, LLC (US) | 2021-08-17 | — | — | US | disclosed |
| US-11091477-B2 | Protein kinase regulators | Madera Therapeutics, LLC (US) | 2021-08-17 | — | — | US | disclosed |
| US-20200181139-A1 | Protein Kinase Regulators | Madera Therapeutics, LLC | 2020-06-11 | — | — | US | disclosed |
| US-20200181139-A1 | Protein Kinase Regulators | Madera Therapeutics, LLC | 2020-06-11 | — | — | US | disclosed |
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004014909-A1 | FUSED TETRAHYDROPYRIDINE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-0621037-B1 | Pyrido-pyrimidinediones, process for their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1999-07-07 | — | — | EP | disclosed |
| US-5556854-A | CARDIOVASCULAR DISORDERS AND/OR NEUROGENERATIVE DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |
| EP-0621037-A1 | Pyrido-pyrimidinediones, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091477-B2 | Protein kinase regulators | MAP3K1, MAP3K6, MAP3K20 | SLC6A5 4650/4885CLPP 1459/4885KDM4E 2313/4885 |
| US-20200181139-A1 | Protein Kinase Regulators | MAP3K1, MAP3K6, MAP3K20 | SLC6A5 4650/4885CLPP 1459/4885KDM4E 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.