Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317872 | 0.90 | TDP1 (0.38) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL8317619 | 0.87 | PTGES2 (0.37) | HTTLMNAPSIP1PPARAHSD11B1 | |
| SCHEMBL8646731 | 0.86 | HSD11B1 (0.38) | MEN1KMT2AMAPTPPARAALDH1A1 | |
| SCHEMBL8651818 | 0.86 | HSD11B1 (0.38) | MEN1KMT2AMAPTPPARAALDH1A1 | |
| SCHEMBL3191672 | 0.85 | TSHR (0.39) | ALDH1A1ABCB1TSHRTDP1 | |
| SCHEMBL3197600 | 0.84 | TDP1 (0.40) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL8320144 | 0.84 | PPARA (0.39) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL8316984 | 0.84 | PPARA (0.39) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4485970 | 0.83 | PSIP1 (0.52) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL63999 | 0.82 | HSD11B1 (0.41) | MEN1KMT2AHTTLMNAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |