Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319646 | 0.90 | MEN1 (0.38) | TDP1ALDH1A1TSHRMEN1MAPT | |
| SCHEMBL3191672 | 0.90 | TSHR (0.39) | TDP1ALDH1A1TSHRABCB1MMP9 | |
| SCHEMBL8322166 | 0.88 | TDP1 (0.35) | TDP1ALDH1A1ABCB1PPARAPSIP1 | |
| SCHEMBL6652822 | 0.85 | TDP1 (0.49) | TDP1ALDH1A1TSHRMEN1MAPT | |
| SCHEMBL7575486 | 0.83 | ALDH1A1 (0.43) | TDP1ALDH1A1MAPTPSIP1ESR2 | |
| SCHEMBL8646731 | 0.82 | HSD11B1 (0.38) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL8651818 | 0.82 | HSD11B1 (0.38) | ALDH1A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL8320144 | 0.81 | PPARA (0.39) | TDP1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL3197600 | 0.81 | TDP1 (0.40) | TDP1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8316984 | 0.81 | PPARA (0.39) | TDP1ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |