Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316984 | 1.00 | PPARA (0.39) | PPARAHSD11B1HTTSMN1; SMN2LMNA | |
| SCHEMBL8321316 | 0.93 | ELANE (0.36) | PPARAHSD11B1SMN1; SMN2CNR2ALDH1A1 | |
| SCHEMBL3197600 | 0.87 | TDP1 (0.40) | PPARAHSD11B1HTTSMN1; SMN2LMNA | |
| SCHEMBL63999 | 0.84 | HSD11B1 (0.41) | PPARAHSD11B1HTTSMN1; SMN2LMNA | |
| SCHEMBL64049 | 0.84 | HSD11B1 (0.41) | PPARAHSD11B1HTTSMN1; SMN2LMNA | |
| SCHEMBL8319646 | 0.84 | MEN1 (0.38) | PPARAHSD11B1HTTSMN1; SMN2LMNA | |
| SCHEMBL8318837 | 0.83 | ALDH1A1 (0.38) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8324855 | 0.83 | ALDH1A1 (0.38) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL207124 | 0.82 | HTR6 (0.46) | SMN1; SMN2LMNAALDH1A1MAPTHTR6 | |
| SCHEMBL65270 | 0.82 | HTT (0.45) | PPARAHTTSMN1; SMN2LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |