Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 16/20 | 0.47 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466205 | 0.80 | ACP1 (0.42) | ACP1 | |
| SCHEMBL27498531 | 0.71 | MEN1 (0.45) | ACP1 | |
| SCHEMBL10900630 | 0.70 | MEN1 (0.63) | — | |
| SCHEMBL27527097 | 0.68 | MIF (0.42) | ADORA3 | |
| SCHEMBL3650858 | 0.66 | GABRA1 (0.52) | ADORA3ACP1 | |
| SCHEMBL27498533 | 0.65 | NPBWR1 (0.46) | — | |
| SCHEMBL6153284 | 0.65 | BACE1 (0.44) | — | |
| SCHEMBL5904565 | 0.65 | BACE1 (0.44) | — | |
| SCHEMBL5904572 | 0.65 | BACE1 (0.44) | — | |
| SCHEMBL5904609 | 0.64 | TP53 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888347-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034893-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-09-25 | — | — | WO | claimed |