Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222039 | 0.78 | LMNA (0.48) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2951668 | 0.77 | ALDH1A1 (0.40) | KMT2ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27920146 | 0.75 | SIGMAR1 (0.51) | MEN1KMT2ALMNASIGMAR1ALDH1A1 | |
| SCHEMBL5778817 | 0.72 | MEN1 (0.56) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL431539 | 0.71 | CYP3A4 (0.56) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6621542 | 0.70 | SIGMAR1 (0.52) | LMNASIGMAR1ALDH1A1POLBGAA | |
| SCHEMBL1344511 | 0.70 | CYP2D6 (0.46) | KMT2ACYP3A4CYP2D6LMNASIGMAR1 | |
| SCHEMBL7534318 | 0.70 | MEN1 (0.47) | MEN1KMT2ACYP2D6LMNAALDH1A1 | |
| SCHEMBL11136854 | 0.70 | SIGMAR1 (0.44) | MEN1KMT2ACYP3A4CYP2D6LMNA | |
| SCHEMBL6953942 | 0.69 | BCHE (0.61) | SIGMAR1ALDH1A1SMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0721948-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| EP-0721948-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| EP-0705828-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |