Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844317 | 0.82 | MEN1 (0.43) | KDM4CMEN1KMT2ASLC6A3HPGD | |
| SCHEMBL17835751 | 0.82 | MEN1 (0.43) | KDM4CMEN1KMT2ASLC6A3HPGD | |
| SCHEMBL17844743 | 0.78 | MEN1 (0.40) | KDM4CMEN1KMT2ASLC6A3HPGD | |
| Hydrochloric Acid SCHEMBL6205586 | 0.75 | KDM4C (0.43) | KDM4CMEN1KMT2ASLC6A3L3MBTL1 | |
| SCHEMBL17846160 | 0.74 | MEN1 (0.41) | KDM4CMEN1KMT2ASLC6A3GAA | |
| SCHEMBL7097200 | 0.74 | EPHX1 (0.43) | KDM4CMEN1KMT2A | |
| SCHEMBL7330307 | 0.74 | MEN1 (0.39) | KDM4CMEN1KMT2ASLC6A3EP300 | |
| SCHEMBL14945274 | 0.74 | SLC6A3 (0.39) | KDM4CMEN1KMT2ASLC6A3HPGD | |
| SCHEMBL14945265 | 0.74 | SLC6A3 (0.39) | KDM4CMEN1KMT2ASLC6A3HPGD | |
| SCHEMBL7215033 | 0.74 | PRMT5 (0.43) | MEN1KMT2ACYP2D6IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621037-B1 | Pyrido-pyrimidinediones, process for their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1999-07-07 | — | — | EP | disclosed |
| US-5556854-A | CARDIOVASCULAR DISORDERS AND/OR NEUROGENERATIVE DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |
| EP-0621037-A1 | Pyrido-pyrimidinediones, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-26 | — | — | EP | disclosed |