Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13720868 | 0.81 | CTSL (0.42) | MAOB | |
| SCHEMBL4022735 | 0.81 | CTSL (0.42) | MAOB | |
| SCHEMBL8112359 | 0.75 | SMN1; SMN2 (0.34) | MAOBHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL21107627 | 0.75 | SMN1; SMN2 (0.34) | MAOBHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL8112362 | 0.75 | SMN1; SMN2 (0.34) | MAOBHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL8318112 | 0.70 | DPP4 (0.36) | MAOBDPP4 | |
| SCHEMBL16244240 | 0.66 | GPBAR1 (0.34) | MAOB | |
| SCHEMBL8317198 | 0.66 | TSHR (0.39) | MAOBSLC6A2SLC6A4SLC6A3DPP4 | |
| SCHEMBL13069786 | 0.66 | MAOB (0.40) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8105017 | 0.66 | SLC6A2 (0.48) | HTR2CSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |