Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318483 | 0.90 | FAAH (0.63) | FAAHDRD4DRD2HTR3A | |
| SCHEMBL8320637 | 0.84 | CHKA (0.64) | DRD4DRD2DRD3 | |
| SCHEMBL27267535 | 0.82 | FAAH (0.58) | FAAH | |
| SCHEMBL8323130 | 0.82 | FAAH (0.48) | FAAH | |
| SCHEMBL3605056 | 0.81 | FAAH (0.74) | FAAH | |
| SCHEMBL16599414 | 0.80 | FAAH (0.57) | FAAH | |
| SCHEMBL3595508 | 0.80 | FAAH (0.56) | FAAH | |
| SCHEMBL13940591 | 0.80 | FAAH (0.56) | FAAH | |
| SCHEMBL27742264 | 0.79 | HTR3A (0.58) | FAAHDRD4NPC1RAB9ADRD2 | |
| SCHEMBL27666048 | 0.79 | HTR3A (0.58) | FAAHDRD4NPC1RAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |