SCHEMBL8323130

SCHEMBL8323130

Brc1[c]ccc(N2CCN(Cc3cnc4ccccc4c3)CC2)c1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 18/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8320213 0.82 FAAH (0.60) FAAH
SCHEMBL15475113 0.81 DRD4 (0.59)
SCHEMBL8323975 0.80 HTR1A (0.46) FAAH
SCHEMBL8318483 0.78 FAAH (0.63) FAAH
SCHEMBL15474649 0.76 DRD4 (0.54)
SCHEMBL27267535 0.74 FAAH (0.58) FAAH
SCHEMBL3595508 0.72 FAAH (0.56) FAAH
SCHEMBL13940591 0.71 FAAH (0.56) FAAH
SCHEMBL27666048 0.71 HTR3A (0.58) FAAH
SCHEMBL27742264 0.71 HTR3A (0.58) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945421-A TREATING PSYCHOSIS AND SCHIZOPHRENIA WARNER-LAMBERT COMPANY (US) 1999-08-31 US disclosed