SCHEMBL8320729

SCHEMBL8320729

Sc1c(OCc2ccccc2)ccnc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.46
LTA4H P09960 1/20 0.46
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
POLB P06746 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
ABCB1 P08183 1/20 0.42
HTR1A P08908 2/20 0.41
DRD2 P14416 1/20 0.41
LIPE Q05469 1/20 0.40
PLAU P00749 2/20 0.40
PLAT P00750 1/20 0.39
PTGER1 P34995 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23723738 0.83 MAPK14 (0.49) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL30013758 0.83 MAPK14 (0.49) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL10819320 0.80 L3MBTL1 (0.61) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL16094113 0.80 MAPK14 (0.49) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL30666902 0.78 POLB (0.44) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL17224562 0.78 MAPT (0.56) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL30666961 0.78 MAPT (0.56) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL2339072 0.77 LTA4H (0.64) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL740590 0.76 GRM2 (0.46) MAPK14LTA4HMAPTMAPK1TDP1
SCHEMBL31328995 0.76 NPC1 (0.49) MAPK14LTA4HPOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869428-A CONTROLLING WEEDS ISHIHARA SANGYO KAISHA LTD. (JP) 1999-02-09 US disclosed
CN-1139109-A Pyridonesulfonylurea compounds, process for their production and herbicides containing them ISHIHARA SANGYO KAISHA (JP) 1997-01-01 CN disclosed
EP-0733629-A1 Pyridonesulfonylurea compounds, process for their production and herbicides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-09-25 EP disclosed