Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649310 | 0.74 | HSP90AA1 (0.37) | KMT2AL3MBTL1HSP90AA1ALDH1A1MEN1 | |
| SCHEMBL8458358 | 0.74 | HSP90AA1 (0.37) | KMT2AL3MBTL1HSP90AA1LMNAALDH1A1 | |
| SCHEMBL8317686 | 0.70 | HSP90AA1 (0.46) | KMT2AL3MBTL1HSP90AA1ALDH1A1GAA | |
| SCHEMBL1508 | 0.70 | HSP90AA1 (0.55) | KMT2AL3MBTL1HSP90AA1ALDH1A1USP2 | |
| SCHEMBL13800708 | 0.70 | HSP90AA1 (0.46) | KMT2AL3MBTL1HSP90AA1ALDH1A1USP2 | |
| Acetic Acid SCHEMBL30721072 | 0.68 | HSP90AA1 (0.53) | KMT2AL3MBTL1HSP90AA1USP2ALOX15 | |
| SCHEMBL178769 | 0.67 | ALDH1A1 (0.48) | KMT2AL3MBTL1LMNAALDH1A1GAA | |
| Triphenylphosphine Oxide SCHEMBL1873876 | 0.66 | KMT2A (0.50) | KMT2AL3MBTL1LMNAALDH1A1USP2 | |
| SCHEMBL7240864 | 0.66 | KMT2A (0.50) | KMT2AL3MBTL1LMNAALDH1A1USP2 | |
| SCHEMBL4968872 | 0.65 | CA2 (0.43) | KMT2AL3MBTL1HSP90AA1ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808129-A | Process for the preparation of novel stabilized phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | claimed |
| US-5856558-A | REACTING 2-FORMYL- OR 2-OXOALKYLIDENETRIPHENYLPHOSPHORANE WITH A CHLORINATING AGENT; HEATING; THEN NUCLEOPHILIC AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |
| US-5808129-A | Process for the preparation of novel stabilized phosphorus ylides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |