Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260942 | 0.87 | SMN1; SMN2 (0.50) | ALDH1A1ESR1KMT2AMEN1MAPT | |
| SCHEMBL18972851 | 0.85 | ESR1 (0.65) | ESR1CES2PTGS2 | |
| SCHEMBL28608248 | 0.84 | ESR1 (0.44) | ALDH1A1ESR1KMT2AMEN1MAPT | |
| SCHEMBL23964325 | 0.81 | ALDH1A1 (0.50) | ALDH1A1ESR1KMT2AMEN1MAPT | |
| SCHEMBL17208791 | 0.81 | CYP19A1 (0.50) | ALDH1A1ESR1KMT2AMEN1MAPT | |
| SCHEMBL28241182 | 0.81 | ESR1 (0.43) | ALDH1A1ESR1KMT2AMEN1MAPT | |
| SCHEMBL31512537 | 0.79 | KMT2A (0.44) | ALDH1A1ESR1KMT2AMEN1MAPT | |
| SCHEMBL15626973 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1GABRA1GABRB1 | |
| SCHEMBL5599378 | 0.79 | ESR1 (0.54) | ALDH1A1ESR1KMT2AMEN1GABRA1 | |
| SCHEMBL4657618 | 0.77 | GABRA1 (0.56) | ALDH1A1KMT2AMEN1GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057798-A | Fluorescent probe, preparation method and application thereof | 徐州医科大学 | 2022-09-16 | — | — | CN | claimed |
| CN-114512719-A | Eutectic solvent-based electrolyte and application thereof | 中国科学院青岛生物能源与过程研究所 | 2022-05-17 | — | — | CN | claimed |
| CN-113801179-A | Beta-galactosidase fluorescent probe, preparation method and application thereof | 华东理工大学 | 2021-12-17 | — | — | CN | claimed |
| CN-118221635-A | Aryl thiophene compound and preparation method and application thereof | 沈阳药科大学 | 2024-06-21 | — | — | CN | disclosed |
| WO-2023219521-A1 | NEW 2-(DIETHYLAMINO)-4,6-DIPHENYLBENZENE-1,3-CARBONITRILE DERIVATIVES, METHOD OF THEIR PRODUCTION, THEIR USE AND NEW PHOTOINITIATING SYSTEMS FOR PHOTOINITIATED CATIONIC, RADICAL, THIOL-ENE AND HYBRID POLYMERIZATION | Politechnika Krakowska im. Tadeusza Kościuszki (PL) | 2023-11-16 | — | — | WO | disclosed |
| CN-116535368-A | Dicyanomethane compound and synthesis method and application thereof | 浙江理工大学嵊州创新研究院有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116514694-A | Preparation method of sulfur ylide compound | 浙江大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-116496191-A | Preparation method of polysubstituted alkenyl thioether compound | 浙江大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-115839028-A | Antibacterial surgical operation suture line and preparation method and application thereof | 华南理工大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-115057798-B | Fluorescent probe, preparation method and application thereof | 徐州医科大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-115057798-A | Fluorescent probe, preparation method and application thereof | 徐州医科大学 | 2022-09-16 | — | — | CN | disclosed |
| US-20120130090-A1 | TRIFLUOROMETHYLTHIOPHENIUM DERIVATIVE SALT, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING TRIFLUOROMETHYL-CONTAINING COMPOUNDS USING THE SAME | TOSOH F-TECH, INC. (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20120065154-A1 | Pyrazolo Pyrimidine Derivatives and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| CN-101041648-B | Inverse type-1,2-cyclopropane derivative and preparation method thereof | UNIV SHANGHAI | 2010-08-18 | — | — | CN | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| CN-101041648-A | Inverse type-1,2-cyclopropane derivative and preparation method thereof | UNIV SHANGHAI (CN) | 2007-09-26 | — | — | CN | disclosed |
| US-5708180-A | CYCLIZATION OF UNSATURATED NITRILE, AMIDE OR OXIME | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5591833-A | WASHABILITY, COMPATIBILITY WITH THERMOPLASTIC RESINS | MILLIKEN RESEARCH CORPORATION (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0529162-A1 | Colorants and intermediates therefor having branched poly(oxyalkylene)moieties, and their manufacture | MILLIKEN RESEARCH CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | ALDH1A1 371/4885ESR1 815/4885KMT2A 3041/4885 |
| US-20120130090-A1 | TRIFLUOROMETHYLTHIOPHENIUM DERIVATIVE SALT, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING TRIFLUOROMETHYL-CONTAINING COMPOUNDS USING THE SAME | TST, CBR3, CYP4B1 | ALDH1A1 3183/4885ESR1 2162/4885KMT2A 1519/4885 |
| US-20120065154-A1 | Pyrazolo Pyrimidine Derivatives and Methods of Use Thereof | DPYD, DHODH, DLD | ALDH1A1 198/4885ESR1 4443/4885KMT2A 3753/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | ALDH1A1 378/4885ESR1 908/4885KMT2A 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.