Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 19/20 | 0.56 |
| ▸ | MMP2 | P08253 | 15/20 | 0.56 |
| ▸ | MMP9 | P14780 | 11/20 | 0.56 |
| ▸ | MMP8 | P22894 | 7/20 | 0.51 |
| ▸ | MMP3 | P08254 | 5/20 | 0.51 |
| ▸ | MMP14 | P50281 | 2/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP10 | P09238 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229769 | 0.90 | MMP9 (0.55) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL6206247 | 0.82 | SCN4A (0.43) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL6701004 | 0.80 | SCN9A (0.41) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL8312493 | 0.77 | MMP13 (0.47) | MMP13MMP2MMP9MMP1MAPT | |
| Hydrochloric Acid SCHEMBL6264619 | 0.77 | MMP13 (0.46) | MMP13MMP2MMP9MMP1MAPT | |
| SCHEMBL5919537 | 0.75 | MMP13 (0.65) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL8334607 | 0.74 | MMP13 (0.67) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL8320080 | 0.74 | SCN9A (0.41) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL6231405 | 0.72 | MMP13 (0.57) | MMP13MMP2MMP9MMP8MMP3 | |
| SCHEMBL5919493 | 0.71 | MMP13 (0.80) | MMP13MMP2MMP9MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |