Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322802 | 0.84 | DRD4 (0.50) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL8322154 | 0.81 | SLC6A4 (0.47) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL8318858 | 0.79 | DRD4 (0.44) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL8320500 | 0.77 | HTR1A (0.47) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL17289123 | 0.75 | FAAH (0.65) | HTR1AHTR7DRD4FAAHMCHR1 | |
| SCHEMBL1331198 | 0.75 | FAAH (0.65) | HTR1AHTR7DRD4FAAHMCHR1 | |
| SCHEMBL8323715 | 0.75 | SLC6A4 (0.54) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL8319517 | 0.75 | FAAH (0.51) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL11785546 | 0.75 | SLC6A4 (0.59) | HTR1AHTR7DRD4DRD2DRD3 | |
| SCHEMBL8323587 | 0.75 | HTR1A (0.55) | HTR1AHTR7DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |