Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786229 | 0.87 | MAPT (0.59) | SLC6A4HTR1AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL8323587 | 0.86 | HTR1A (0.55) | FAAHHTR7HTR1AMAPTKDM4E | |
| SCHEMBL17289123 | 0.84 | FAAH (0.65) | FAAHHTR7HTR1AMAPTHRH3 | |
| SCHEMBL1331198 | 0.84 | FAAH (0.65) | FAAHHTR7HTR1AMAPTHRH3 | |
| SCHEMBL8319517 | 0.84 | FAAH (0.51) | FAAHHTR7HTR1AMAPTSMN1; SMN2 | |
| SCHEMBL8322802 | 0.84 | DRD4 (0.50) | SLC6A4FAAHHTR7HTR1AMAPT | |
| SCHEMBL1331611 | 0.80 | FAAH (0.58) | FAAHHTR7HTR1AMAPTSMN1; SMN2 | |
| SCHEMBL13041008 | 0.80 | FAAH (0.58) | FAAHHTR7HTR1AMAPTSMN1; SMN2 | |
| SCHEMBL1331766 | 0.80 | HRH3 (0.63) | FAAHHTR7HTR1AMAPTSMN1; SMN2 | |
| SCHEMBL6584608 | 0.79 | FAAH (0.60) | FAAHHTR7HTR1AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |