Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322125 | 0.82 | L3MBTL1 (0.46) | KDM4EPTAFR | |
| SCHEMBL7499604 | 0.81 | STING1 (0.49) | — | |
| SCHEMBL8321832 | 0.78 | GAA (0.50) | PTAFR | |
| SCHEMBL8565849 | 0.76 | PTAFR (0.47) | PTAFR | |
| SCHEMBL9691244 | 0.76 | KMT2A (0.57) | KDM4EALDH1A1PTAFR | |
| SCHEMBL8317845 | 0.75 | PTAFR (0.44) | PTAFR | |
| SCHEMBL8883493 | 0.74 | PTAFR (0.51) | PTAFR | |
| SCHEMBL9691929 | 0.74 | PTAFR (0.45) | PTAFR | |
| SCHEMBL6157116 | 0.74 | GPR119 (0.48) | KDM4E | |
| SCHEMBL8882903 | 0.73 | PTAFR (0.49) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866588-A | DUAL HISTAMINE (H1) AND PLATELET ACTIVATING FACTOR (PAF) RECEPTOR ANTAGONISTS. | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 1999-02-02 | — | — | US | disclosed |