Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320581 | 0.79 | NPSR1 (0.48) | NPSR1KDM4ESYKLMNAALDH1A1 | |
| SCHEMBL8322607 | 0.73 | MEN1 (0.43) | NPSR1KDM4EALDH1A1TRPV1MEN1 | |
| SCHEMBL8324351 | 0.73 | MAPT (0.46) | KDM4ELMNAALDH1A1MEN1MAPT | |
| SCHEMBL8460257 | 0.70 | NPSR1 (0.46) | NPSR1KDM4ECASRSYKLMNA | |
| SCHEMBL8321791 | 0.70 | L3MBTL1 (0.39) | NPSR1KDM4ESYKALDH1A1TRPV1 | |
| SCHEMBL8462289 | 0.70 | MAPT (0.47) | NPSR1KDM4ESYKTRPV1HIF1A | |
| SCHEMBL8522571 | 0.68 | ADORA3 (0.47) | NPSR1KDM4ESYKTRPV1HIF1A | |
| SCHEMBL8523766 | 0.66 | KDM4E (0.39) | KDM4ELMNAALDH1A1MEN1MAPT | |
| Water SCHEMBL8326580 | 0.66 | MAPT (0.38) | NPSR1KDM4ESYKTRPV1HIF1A | |
| SCHEMBL8328108 | 0.65 | MAPT (0.40) | NPSR1KDM4ESYKTRPV1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888347-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034893-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-09-25 | — | — | WO | disclosed |