Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321791 | 0.85 | L3MBTL1 (0.39) | NPSR1KDM4ESYKTRPV1ALDH1A1 | |
| SCHEMBL8462289 | 0.85 | MAPT (0.47) | NPSR1KDM4ESYKTRPV1MPI | |
| SCHEMBL8324852 | 0.84 | GAA (0.53) | NPSR1KDM4ESYKLMNAADORA3 | |
| SCHEMBL8460257 | 0.83 | NPSR1 (0.46) | NPSR1KDM4ESYKPGRTRPV1 | |
| SCHEMBL8523766 | 0.81 | KDM4E (0.39) | KDM4ELMNAPOLBALDH1A1KMT2A | |
| SCHEMBL8322601 | 0.79 | NPSR1 (0.41) | NPSR1KDM4ESYKTRPV1LMNA | |
| SCHEMBL8322607 | 0.77 | MEN1 (0.43) | NPSR1KDM4ETRPV1ALDH1A1KMT2A | |
| SCHEMBL8324351 | 0.77 | MAPT (0.46) | KDM4ELMNAPOLBALDH1A1KMT2A | |
| SCHEMBL8522571 | 0.76 | ADORA3 (0.47) | NPSR1KDM4ESYKPGRTRPV1 | |
| SCHEMBL8328108 | 0.72 | MAPT (0.40) | NPSR1KDM4ESYKTRPV1MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888347-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034893-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-09-25 | — | — | WO | disclosed |