Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448057 | 0.85 | ALDH1A1 (0.48) | ALDH1A1EGFRHTTALDH5A1ABAT | |
| SCHEMBL10889357 | 0.84 | KMT2A (0.65) | ALDH1A1SMN1; SMN2MAPK1HPGDMEN1 | |
| SCHEMBL3801985 | 0.84 | HTT (0.68) | ALDH1A1EGFRHTTALDH5A1ABAT | |
| SCHEMBL614967 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2MAPK1HPGD | |
| SCHEMBL5881545 | 0.83 | LMNA (0.63) | ALDH1A1HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL30480689 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2MAPK1HPGD | |
| SCHEMBL18822434 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2MAPK1HPGD | |
| SCHEMBL29780113 | 0.83 | LMNA (0.63) | ALDH1A1HTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL29780105 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2MAPK1HPGD | |
| SCHEMBL6975312 | 0.82 | MAPT (0.54) | ALDH1A1EGFRHTTALDH5A1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620809-B2 | Useful in treating or in preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-09-16 | — | — | US | disclosed |
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | LES LABORATOIRES SERVIER (FR) | 2001-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | MTNR1A, MTNR1B, SQOR | ALDH1A1 79/4885EGFR 4752/4885HTT 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.