Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322879 | 0.93 | MRGPRX4 (0.38) | PPIAPTGER1MRGPRX4MTNR1AMTNR1B | |
| SCHEMBL8324638 | 0.81 | MRGPRX4 (0.44) | PTGER1MRGPRX4 | |
| SCHEMBL8113906 | 0.72 | MRGPRX4 (0.50) | PPIAPTGER1MRGPRX4PTGDR2PTGER4 | |
| SCHEMBL8409660 | 0.71 | HTR1A (0.59) | PTGER1MRGPRX4FFAR1FFAR4 | |
| SCHEMBL8678841 | 0.71 | PTGER1 (0.47) | PPIAPTGER1MRGPRX4PTGDR2PTGER4 | |
| SCHEMBL5089130 | 0.71 | MRGPRX4 (0.53) | PPIAPTGER1MRGPRX4PTGDR2PTGER4 | |
| Hydrochloric Acid SCHEMBL5098921 | 0.70 | MRGPRX4 (0.52) | PPIAPTGER1MRGPRX4PTGDR2PTGER4 | |
| SCHEMBL8318509 | 0.69 | MRGPRX4 (0.43) | PTGER1MRGPRX4 | |
| SCHEMBL9057884 | 0.69 | CCR5 (0.42) | PTGER1 | |
| SCHEMBL8409628 | 0.68 | MRGPRX4 (0.57) | PTGER1MRGPRX4MTNR1AMTNR1BPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |