Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324470 | 0.85 | PTGER1 (0.48) | PTGER1FOLH1 | |
| SCHEMBL8326795 | 0.84 | HTR1A (0.54) | PTGER1FOLH1 | |
| SCHEMBL8322759 | 0.81 | PPIA (0.39) | MRGPRX4PTGER1 | |
| SCHEMBL8322879 | 0.79 | MRGPRX4 (0.38) | MRGPRX4PTGER1 | |
| SCHEMBL8678841 | 0.79 | PTGER1 (0.47) | MRGPRX4PTGER1FOLH1XDHMAOB | |
| SCHEMBL8409660 | 0.78 | HTR1A (0.59) | MRGPRX4PTGER1MAOB | |
| SCHEMBL8409836 | 0.78 | MRGPRX4 (0.56) | MRGPRX4PTGER1FOLH1 | |
| SCHEMBL9057884 | 0.77 | CCR5 (0.42) | PTGER1 | |
| SCHEMBL1647357 | 0.77 | FOLH1 (0.62) | MRGPRX4PTGER1FOLH1XDHMAOB | |
| SCHEMBL8318509 | 0.76 | MRGPRX4 (0.43) | MRGPRX4PTGER1XDHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |