Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320585 | 0.76 | CDC7 (0.39) | CDC7CDK2MAPTALDH1A1 | |
| SCHEMBL8324323 | 0.74 | ALDH1A1 (0.34) | CDC7CDK2PDE2AALDH1A1 | |
| SCHEMBL8324003 | 0.72 | CDC7 (0.36) | CDC7CDK2MAPTALDH1A1 | |
| SCHEMBL8319454 | 0.72 | MAT2A (0.42) | CDC7CDK2CYP19A1MAPTALDH1A1 | |
| SCHEMBL8324278 | 0.70 | CYP19A1 (0.51) | CYP19A1MAPTNPC1ALDH1A1HTT | |
| SCHEMBL10348129 | 0.69 | ALDH1A1 (0.42) | PDE2AMAPTNPC1ALDH1A1 | |
| SCHEMBL6656027 | 0.68 | CYP11B1 (0.42) | CYP19A1PDE2APDE10AKIF11KDR | |
| SCHEMBL5661243 | 0.67 | CDC7 (0.58) | CDC7CDK2CYP19A1PDE2APDE10A | |
| SCHEMBL8323009 | 0.67 | HSD17B10 (0.42) | HSP90AA1MAPTALDH1A1 | |
| SCHEMBL1149905 | 0.66 | CYP19A1 (0.53) | CDC7CDK2CYP19A1TGFBR1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-5451566-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |