Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321709 | 0.78 | KIF11 (0.33) | ALDH1A1PKMPDE2ASCN9A | |
| SCHEMBL8323045 | 0.74 | CDC7 (0.40) | ALDH1A1CDC7CDK2PDE2A | |
| SCHEMBL18372285 | 0.68 | BIRC5 (0.42) | MEN1KMT2AATML3MBTL1 | |
| SCHEMBL8320585 | 0.67 | CDC7 (0.39) | ALDH1A1CDC7CDK2PKMSCN9A | |
| SCHEMBL8323009 | 0.65 | HSD17B10 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL8324003 | 0.63 | CDC7 (0.36) | ALDH1A1CDC7CDK2CYP2C9CYP2C19 | |
| SCHEMBL8319454 | 0.63 | MAT2A (0.42) | ALDH1A1CDC7CDK2CYP1A2CYP2C19 | |
| SCHEMBL987880 | 0.62 | P2RX3 (0.36) | CDC7CDK2PDE2ACYP2D6CYP2C9 | |
| SCHEMBL987389 | 0.62 | GRIK1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10348129 | 0.61 | ALDH1A1 (0.42) | ALDH1A1PKMPDE2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| EP-0729470-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-04 | — | — | EP | disclosed |
| US-5451566-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |