SCHEMBL7212890

SCHEMBL7212890

CCS(=O)(=O)Nc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1C#N

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGR P06401 8/20 0.39
AR P10275 2/20 0.36
BRD4 O60885 1/20 0.36
BCAT2 O15382 7/20 0.35
BCAT1 P54687 7/20 0.35
PSIP1 O75475 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8323113 0.90 PGR (0.35) PGRARBCAT2BCAT1
SCHEMBL8853791 0.90 BCAT2 (0.35) PGRBCAT2BCAT1
SCHEMBL5868194 0.89 PGR (0.35) PGRARBRD4BCAT2BCAT1
SCHEMBL8466083 0.87 BCAT2 (0.34) PGRBCAT2BCAT1
SCHEMBL8319442 0.87 PGR (0.41) PGRARBRD4BCAT2BCAT1
SCHEMBL8853375 0.85 JAK2 (0.33) ARBRD4BCAT2BCAT1
SCHEMBL7833797 0.85 PSIP1 (0.33) PGRBRD4PSIP1
SCHEMBL7987004 0.85 PSIP1 (0.33) PGRBRD4PSIP1
SCHEMBL7653459 0.83 BCAT2 (0.35) ARBCAT2BCAT1
SCHEMBL8190792 0.83 AR (0.39) PGRARBRD4BCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617281-B1 Substituted acylamino phenyl uracils BAYER AKTIENGESELLSCHAFT (DE) 2003-09-09 US disclosed
US-6331628-B1 REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed
US-6228809-B1 SELECTIVE CONTROL OF MONOCOTYLEDONOUS AND DICOTYLEDONOUS WEEDS IN MONOCOTYLEDONOUS CROPS PRE- AND POST-EMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 2001-05-08 US disclosed
US-5990044-A Selective herbicides based on aryl uracils BAYER AKTIENGESELLSCHAFT (DE) 1999-11-23 US disclosed
US-5900483-A Process for the separation of phenyluracil compounds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-05-04 US disclosed
US-5681794-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1997-10-28 US disclosed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
WO-1997001542-A1 SUBSTITUTED CARBONYLAMINOPHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed
US-5593945-A HERBICIDES AND CHEMICAL INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
WO-1996035679-A1 SUBSTITUTED AMINOPHENYLURACILS AS HERBICIDES AND INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-14 WO disclosed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP disclosed