Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329019 | 0.83 | ITGB3 (0.45) | PTGDR2CACNA1GCACNA1BCACNA1CTDP1 | |
| SCHEMBL16186533 | 0.82 | CACNA1B (0.66) | CACNA1GCACNA1BCACNA1CTDP1MAOB | |
| SCHEMBL3370001 | 0.82 | HSD17B10 (0.49) | MAOBALDH1A1GRIN2BNTRK1NTRK2 | |
| SCHEMBL7330117 | 0.81 | RXFP1 (0.50) | PTGDR2TDP1ITGB3ITGAVALDH1A1 | |
| SCHEMBL6951310 | 0.78 | ITGB3 (0.48) | ITGB3ITGAVALDH1A1 | |
| SCHEMBL6945050 | 0.76 | ITGB3 (0.47) | TDP1ITGB3ITGAVALDH1A1GRIN2B | |
| SCHEMBL8363353 | 0.74 | NPC1 (0.37) | TDP1ITGB3ITGAVGRIN2B | |
| SCHEMBL8324887 | 0.74 | CHRNB2 (0.41) | PTGDR2ALDH1A1 | |
| SCHEMBL8323937 | 0.74 | ITGB3 (0.45) | TDP1ITGB3ITGAVCACNA1HALDH1A1 | |
| SCHEMBL6951174 | 0.74 | PRMT5 (0.46) | TDP1CYP2C9ITGB3ITGAVALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |