Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951174 | 0.82 | PRMT5 (0.46) | ITGB3ITGAVTDP1ALDH1A1KMT2A | |
| SCHEMBL6943657 | 0.81 | CACNA1G (0.57) | ITGB3ITGAVTDP1ALDH1A1CHEK1 | |
| SCHEMBL8324887 | 0.80 | CHRNB2 (0.41) | ALDH1A1MMP2MMP9KMT2ANPC1 | |
| SCHEMBL6945050 | 0.80 | ITGB3 (0.47) | ITGB3ITGAVTDP1ALDH1A1GRIN2B | |
| SCHEMBL8326056 | 0.78 | PTGDR2 (0.45) | ITGB3ITGAVKMT2A | |
| SCHEMBL8329019 | 0.77 | ITGB3 (0.45) | ITGB3ITGAVTDP1LMNAKMT2A | |
| SCHEMBL7330117 | 0.76 | RXFP1 (0.50) | ITGB3ITGAVTDP1ALDH1A1KMT2A | |
| SCHEMBL2313323 | 0.75 | CACNA1H (0.46) | LMNAKMT2APARP1CACNA1H | |
| SCHEMBL856557 | 0.74 | ALDH1A1 (0.52) | TDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL6951310 | 0.74 | ITGB3 (0.48) | ITGB3ITGAVALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |