Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330117 | 0.86 | RXFP1 (0.50) | ITGB3ITGAVTDP1SMN1; SMN2MAPT | |
| SCHEMBL6951310 | 0.83 | ITGB3 (0.48) | ITGB3ITGAVSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL8323304 | 0.83 | PTGDR2 (0.50) | ITGB3ITGAVTDP1GRIN2BPTGDR2 | |
| SCHEMBL16186536 | 0.78 | CACNA1B (0.58) | ITGB3ITGAVTDP1MAPTPDE10A | |
| SCHEMBL8363353 | 0.78 | NPC1 (0.37) | ITGB3ITGAVTDP1SMN1; SMN2MAPT | |
| SCHEMBL8324887 | 0.77 | CHRNB2 (0.41) | SMN1; SMN2MAPTMAPK1TSHRATM | |
| SCHEMBL6945050 | 0.77 | ITGB3 (0.47) | ITGB3ITGAVTDP1MAPTMAPK1 | |
| SCHEMBL8323937 | 0.77 | ITGB3 (0.45) | ITGB3ITGAVTDP1GRIN2BLMNA | |
| SCHEMBL6951174 | 0.77 | PRMT5 (0.46) | ITGB3ITGAVTDP1PKMGAA | |
| SCHEMBL7331804 | 0.77 | L3MBTL1 (0.40) | TDP1SMN1; SMN2GRIN2BPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |