Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383185 | 0.90 | AGTR1 (0.46) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL976147 | 0.89 | LMNA (0.47) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL27347057 | 0.84 | LMNA (0.36) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL9235857 | 0.83 | MEN1 (0.42) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL9025603 | 0.81 | MEN1 (0.41) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL27373084 | 0.80 | AGTR1 (0.41) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL7195878 | 0.78 | LMNA (0.43) | LMNAAGTR1AGTR2ALDH1A1HTT | |
| SCHEMBL7196989 | 0.78 | AGTR1 (0.41) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL9025749 | 0.78 | AGTR1 (0.43) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 | |
| SCHEMBL3256000 | 0.78 | CA1 (0.43) | LMNAHSD17B10AGTR1AGTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589665-B1 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA CHEMICAL IND CO LTD (JP) | 1999-11-17 | — | — | EP | claimed |
| EP-0589665-A2 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-30 | — | — | EP | claimed |
| CN-102311426-B | Preparation method of olmesartan intermediate | NINGBO MEINUOHUA PHARMACEUTICAL CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-102311426-A | Preparation method of olmesartan intermediate | NINGBO MEINUOHUA PHARMACEUTICAL CO LTD | 2012-01-11 | — | — | CN | disclosed |
| CN-1115337-C | Pyrimidinone derivs. | BORYUNG PHARM (KR) | 2003-07-23 | — | — | CN | disclosed |
| EP-0589665-B1 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA CHEMICAL IND CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| CN-1160395-A | Pyrimidone derivatives | BORYUNG PHARM (KR) | 1997-09-24 | — | — | CN | disclosed |
| US-5401736-A | Angiotensis II antagonists | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0589665-A2 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-30 | — | — | EP | disclosed |