SCHEMBL8323852

SCHEMBL8323852

COC(=O)c1c(C23CC4CC(CC(C4)C2)C3)cc2ccccc2c1-c1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
CNR2 P34972 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
HIF1A Q16665 2/20 0.37
EPAS1 Q99814 2/20 0.37
IKBKB O14920 1/20 0.37
MDH1 P40925 1/20 0.37
MDH2 P40926 1/20 0.37
EP300 Q09472 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8323848 0.74 KMT2A (0.50) MEN1KMT2AMAPTALDH1A1HPGD
Anisole SCHEMBL8573067 0.73 KMT2A (0.38) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8322639 0.72 KMT2A (0.47) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL29929549 0.72 KMT2A (0.47) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8766838 0.72 MEN1 (0.35) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8322327 0.71 MEN1 (0.46) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL17323573 0.69 MEN1 (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8322293 0.69 RARB (0.43) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL9318192 0.69 MEN1 (0.46) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8455573 0.68 SLC6A3 (0.42) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942531-A Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) 1999-08-24 US disclosed