Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.35 |
| ▸ | RARG | P13631 | 4/20 | 0.35 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766827 | 0.77 | WDR5 (0.40) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL9318119 | 0.76 | RARB (0.44) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL28544087 | 0.74 | DRD2 (0.38) | KDM4EFAAHDRD2 | |
| SCHEMBL8322327 | 0.73 | MEN1 (0.46) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL17323573 | 0.72 | MEN1 (0.45) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL29929549 | 0.72 | KMT2A (0.47) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL8322639 | 0.72 | KMT2A (0.47) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL8323852 | 0.72 | MEN1 (0.41) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL8322293 | 0.71 | RARB (0.43) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL7759671 | 0.71 | RARG (0.53) | MEN1KMT2ARARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584191-B1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | CIRD GALDERMA (FR) | 1997-08-13 | — | — | EP | disclosed |