Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | MDH1 | P40925 | 2/20 | 0.42 |
| ▸ | MDH2 | P40926 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318192 | 0.74 | MEN1 (0.46) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL8323852 | 0.74 | MEN1 (0.41) | KMT2AMEN1MAPTHIF1AEPAS1 | |
| SCHEMBL30356865 | 0.72 | MAPT (0.61) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL593520 | 0.72 | MAPT (0.61) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL21194961 | 0.71 | GPR35 (0.43) | KMT2AMEN1GAAHIF1AEPAS1 | |
| SCHEMBL2710580 | 0.71 | MEN1 (0.76) | KMT2AMEN1MAPTPOLBGAA | |
| SCHEMBL8766827 | 0.71 | WDR5 (0.40) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL16384835 | 0.70 | MAPT (0.56) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL3976009 | 0.69 | MEN1 (0.46) | KMT2AMEN1POLBGAAGFER | |
| SCHEMBL22500467 | 0.69 | MEN1 (0.63) | KMT2AMEN1MAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942531-A | Phenolic/naphtholic retinoids for promoting skin/exoskeleton pigmentation | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 1999-08-24 | — | — | US | disclosed |