Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913 | 0.89 | — | — | |
| Butane SCHEMBL4463544 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL15652979 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| Potassium SCHEMBL183183 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| SCHEMBL6504995 | 0.84 | TSHR (0.55) | ALDH1A1TSHRTDP1 | |
| Methane SCHEMBL30637 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| Water SCHEMBL8067978 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| SCHEMBL775104 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| Ethane SCHEMBL353672 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| SCHEMBL30933076 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022052936-A1 | ARYL PROPIONIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION, AND METHOD FOR PREPARATION THEREOF AND APPLICATION THEREOF | 南京海融医药科技股份有限公司 | 2022-03-17 | — | — | WO | claimed |
| US-20230002334-A1 | TRPM8 MODULATORS | GIVAUDAN SA (CH) | 2023-01-05 | — | — | US | disclosed |
| EP-4065566-A1 | TRPM8 MODULATORS | Givaudan SA (CH) | 2022-10-05 | — | — | EP | disclosed |
| CN-114761385-A | TRPM8 modulators | 奇华顿股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2021105261-A1 | TRPM8 MODULATORS | GIVAUDAN SA (CH) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021102896-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2021-06-03 | — | — | WO | disclosed |
| CN-107074829-B | For inhibiting microsomal prostaglandin E2Novel methyl-piperidine compounds of synthetase-1 | 伊莱利利公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-2020119507-A1 | METHOD FOR CONTINUOUSLY PREPARING 5-CITALOPRAM DIOL | 浙江华海药业股份有限公司 | 2020-06-18 | — | — | WO | disclosed |
| WO-2020010643-A1 | METHOD FOR SYNTHESIZING VALSARTAN | 浙江华海药业股份有限公司 | 2020-01-16 | — | — | WO | disclosed |
| US-20180250282-A1 | Novel Methyl-Piperidine Compounds Useful for Inhibiting Microsomal Prostaglandin E2 Synthase-1 | LILLY CO ELI (US) | 2018-09-06 | — | — | US | disclosed |
| US-9962375-B2 | Methyl-piperidine compounds useful for inhibiting microsomal prostaglandin E2 synthase-1 | ELI LILLY AND COMPANY (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170326128-A1 | Novel Methyl-Piperidine Compounds Useful for Inhibiting Microsomal Prostaglandin E2 Synthase-1 | ELI LILLY AND COMPANY | 2017-11-16 | — | — | US | disclosed |
| US-5902773-A | PESTICIDES AND FUNGICIDES FORMED BY MULTISTAGE REACTIONS, WITTIG REACTION WITH BENZALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326128-A1 | Novel Methyl-Piperidine Compounds Useful for Inhibiting Microsomal Prostaglandin E2 Synthase-1 | PTGS1, PTGES, PTGER1 | ALDH1A1 46/4885TSHR 3150/4885TDP1 2452/4885 |
| US-20230002334-A1 | TRPM8 MODULATORS | TRPM8, TRPM7, TRPM2 | ALDH1A1 2157/4885TSHR 1377/4885TDP1 3842/4885 |
| US-20180250282-A1 | Novel Methyl-Piperidine Compounds Useful for Inhibiting Microsomal Prostaglandin E2 Synthase-1 | PTGS1, PTGES, PTGER1 | ALDH1A1 50/4885TSHR 3194/4885TDP1 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.