Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326586 | 0.81 | ALDH1A1 (0.40) | AOC3ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL8323908 | 0.76 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KDM4ELMNAGRIA2 | |
| SCHEMBL2760401 | 0.74 | KDM4E (0.44) | ALDH1A1L3MBTL1KDM4ELMNAGRIA2 | |
| SCHEMBL3798203 | 0.72 | RXFP1 (0.41) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL479900 | 0.72 | KDM4E (0.51) | ALDH1A1L3MBTL1KDM4ELMNAMEN1 | |
| SCHEMBL24380727 | 0.66 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1KDM4ELMNAMEN1 | |
| SCHEMBL16402408 | 0.65 | GAA (0.39) | ALDH1A1L3MBTL1KDM4ELMNAGRIA2 | |
| SCHEMBL12281004 | 0.65 | AOC3 (0.62) | AOC3ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL9537012 | 0.63 | GAA (0.40) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9535401 | 0.63 | GAA (0.40) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |