Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548535 | 0.89 | CYP3A4 (0.60) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL966908 | 0.86 | CYP3A4 (0.55) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL29502024 | 0.86 | CYP3A4 (0.55) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL405476 | 0.86 | CD44 (0.48) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL28606707 | 0.83 | CYP3A4 (0.60) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL29838774 | 0.83 | ALDH1A1 (0.40) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL1479690 | 0.83 | ALDH1A1 (0.40) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL832549 | 0.82 | KDM1A (0.41) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL9073257 | 0.81 | CYP3A4 (0.50) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL203096 | 0.79 | KDM1A (0.52) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021463-B2 | Therapeutic inhibitory compounds | ATTUNE PHARMACEUTICALS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| EP-3162802-B1 | 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME | NIHON MEDIPHYSICS CO LTD (JP) | 2020-08-19 | — | — | EP | disclosed |
| US-20200031800-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2020-01-30 | — | — | US | disclosed |
| US-20200031799-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2020-01-30 | — | — | US | disclosed |
| US-10023557-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-07-17 | — | — | US | disclosed |
| WO-2018089373-A9 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| EP-2793578-B1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | disclosed |
| WO-2018089373-A2 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20180051021-A1 | BICYCLIC KETONE SULFONAMIDE COMPOUNDS | AMGEN INC. (US) | 2018-02-22 | — | — | US | disclosed |
| EP-3162802-A1 | 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-20110033417-A1 | 2,3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | MERCK SHARP & DOHME CORP. | 2011-02-10 | — | — | US | disclosed |
| US-20100322901-A1 | 5, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF | SCHERING CORPORATION | 2010-12-23 | — | — | US | disclosed |
| US-7626014-B2 | Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety | ALNYLAM PHARMACEUTICALS (US) | 2009-12-01 | — | — | US | disclosed |
| WO-2009032123-A2 | TETRACYCLIC INDOLE DERIVATIVES AND THEIR USE FOR TREATING OR PREVENTING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2009-03-12 | — | — | WO | disclosed |
| EP-0288493-B1 | 3-HALOGEN SUCCINIMIDES | DOWELANCO (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4977183-A | 3-halosuccinimides and plant fungicidal use thereof | THE DOW CHEMICAL COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4900840-A | 3-halosuccinimides | THE DOW CHEMICAL COMPANY (US) | 1990-02-13 | — | — | US | disclosed |
| EP-0288493-A1 | 3-HALOGEN SUCCINIMIDES. | DOW CHEMICAL CO (US) | 1988-11-02 | — | — | EP | disclosed |
| WO-1988002747-A1 | 3-HALOGEN SUCCINIMIDES | THE DOW CHEMICAL COMPANY (US) | 1988-04-21 | — | — | WO | disclosed |
| US-4173645-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110033417-A1 | 2,3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | IDO2, IDO1, IRF3 | CYP3A4 666/4885TSHR 3796/4885MAPK1 4340/4885 |
| US-20200031800-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | CYP3A4 3159/4885TSHR 4687/4885MAPK1 1148/4885 |
| US-20200031799-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | CYP3A4 3159/4885TSHR 4687/4885MAPK1 1148/4885 |
| US-10023557-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | CYP3A4 3159/4885TSHR 4687/4885MAPK1 1148/4885 |
| US-20180051021-A1 | BICYCLIC KETONE SULFONAMIDE COMPOUNDS | TRPV1, TRPA1, KCNJ11 | CYP3A4 993/4885TSHR 3998/4885MAPK1 305/4885 |
| US-20100322901-A1 | 5, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF | IDO1, IDO2, TPH1 | CYP3A4 90/4885TSHR 3201/4885MAPK1 4217/4885 |
| US-11021463-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | CYP3A4 3159/4885TSHR 4687/4885MAPK1 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.