Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 6/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320500 | 0.87 | HTR1A (0.47) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL8324074 | 0.86 | FAAH (0.47) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL8319517 | 0.83 | FAAH (0.51) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL8323130 | 0.80 | FAAH (0.48) | FAAH | |
| SCHEMBL1331198 | 0.78 | FAAH (0.65) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL17289123 | 0.78 | FAAH (0.65) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL15475113 | 0.77 | DRD4 (0.59) | HTR1AHTR7DRD4HTR2ADRD2 | |
| SCHEMBL8323587 | 0.77 | HTR1A (0.55) | HTR1AHTR7FAAHHRH3DRD4 | |
| SCHEMBL27609044 | 0.75 | DRD4 (0.62) | HTR1AHTR7MCHR1DRD4HTR2A | |
| SCHEMBL8322802 | 0.75 | DRD4 (0.50) | HTR1AHTR7FAAHDRD4ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |