Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323117 | 0.90 | HDAC1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL8323886 | 0.87 | NR1H4 (0.40) | BRS3ESR1ABCG2HDAC3HDAC1 | |
| SCHEMBL8319501 | 0.81 | THRB (0.54) | TBXAS1AKR1C3BRS3KDM4EALDH1A1 | |
| SCHEMBL8324383 | 0.80 | ESR1 (0.51) | TBXAS1AKR1C3BRS3KDM4EALDH1A1 | |
| SCHEMBL14609702 | 0.75 | RECQL (0.51) | RECQLAKR1C3KDM4EALDH1A1HPGD | |
| SCHEMBL8322760 | 0.73 | TBXAS1 (0.48) | TBXAS1BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL2772402 | 0.68 | TBXAS1 (0.71) | RECQLTBXAS1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL459101 | 0.68 | TBXAS1 (0.71) | RECQLTBXAS1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8322805 | 0.68 | BRS3 (0.48) | TBXAS1BRS3KDM4EALDH1A1HPGD | |
| SCHEMBL8322757 | 0.67 | RNASEH1 (0.52) | TBXAS1KDM4EALDH1A1SMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |