Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 8/20 | 0.74 |
| ▸ | FAAH | O00519 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612752 | 0.86 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19628792 | 0.86 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612519 | 0.82 | FAAH (1.00) | NAAAFAAH | |
| SCHEMBL11769070 | 0.82 | POLB (0.64) | NAAAFAAHPOLB | |
| SCHEMBL16335477 | 0.82 | NAAA (0.54) | NAAAFAAHPOLB | |
| SCHEMBL19612619 | 0.80 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL16193763 | 0.80 | POLB (0.78) | NAAAFAAHPOLB | |
| SCHEMBL14325303 | 0.79 | NAAA (0.54) | NAAAFAAH | |
| SCHEMBL11705033 | 0.78 | NAAA (0.69) | NAAAFAAHPOLB | |
| SCHEMBL8778553 | 0.77 | HPGD (0.51) | NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074788-B | Substituted heterocyclic derivatives, preparation method and application thereof | 厦门大学 | 2019-09-20 | — | — | CN | disclosed |
| US-9598383-B2 | Reactive oxygen species-based prodrugs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-21 | — | — | US | disclosed |
| CN-104356082-B | One class substituted heterocycle derivant and preparation method thereof | 厦门大学 | 2016-07-13 | — | — | CN | disclosed |
| US-20150005352-A1 | REACTIVE OXYGEN SPECIES-BASED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-01 | — | — | US | disclosed |
| US-5972237-A | USED AS COLD BLEACH ACTIVATORS OR OPTICAL BRIGHTENERS IN DETERGENTS, CLEANERS AND BLEACHES AND IN DISINFECTANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0826025-A1 | USE OF HETEROCYCLIC COMPOUNDS AS ACTIVATORS FOR INORGANIC PEROXY COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036686-A1 | USE OF HETEROCYCLIC COMPOUNDS AS ACTIVATORS FOR INORGANIC PEROXY COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-21 | — | — | WO | disclosed |
| US-4505859-A | Preparation of 2-haloethylamides | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4007168-A | Process for preparing penicillins derivatives | PALOMO COLL A L | 1977-02-08 | — | — | US | disclosed |
| US-3947465-A | 3-Alkylsilyl-2-oxazolidonone compounds and synthesis thereof | PALOMO COLL A L | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005352-A1 | REACTIVE OXYGEN SPECIES-BASED PRODRUGS | ROS1, NOX4, NOX1 | NAAA 2323/4885FAAH 4085/4885POLB 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.