Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 7/20 | 1.00 |
| ▸ | FAAH | O00519 | 5/20 | 1.00 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324037 | 0.86 | NAAA (0.74) | NAAAFAAH | |
| SCHEMBL19612519 | 0.82 | FAAH (1.00) | NAAAFAAHMEN1RAB9AKMT2A | |
| SCHEMBL19612536 | 0.77 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL19612527 | 0.76 | NAAA (1.00) | NAAAFAAH | |
| SCHEMBL29246517 | 0.74 | FAAH (0.59) | NAAAFAAHMEN1RAB9AKMT2A | |
| SCHEMBL29139053 | 0.74 | FAAH (0.59) | NAAAFAAHMEN1RAB9AKMT2A | |
| SCHEMBL19612752 | 0.73 | NAAA (1.00) | NAAAFAAHMEN1KMT2A | |
| SCHEMBL28504587 | 0.73 | HPGD (0.72) | NAAAFAAHHPGDSLC6A7MEN1 | |
| SCHEMBL28664420 | 0.73 | NAAA (0.57) | NAAAFAAHMEN1KMT2A | |
| SCHEMBL23440313 | 0.72 | HPGD (0.71) | HPGDSLC6A7MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174015-B2 | Substituted heterocyclic derivative, preparation method and use thereof | XIAMEN UNIVERSITY (CN) | 2019-01-08 | — | — | US | disclosed |
| US-20170334896-A1 | Substituted Heterocyclic Derivative, Preparation Method And Use Thereof | XIAMEN UNIVERSITY (CN) | 2017-11-23 | — | — | US | disclosed |
| US-20170334896-A1 | Substituted Heterocyclic Derivative, Preparation Method And Use Thereof | XIAMEN UNIVERSITY (CN) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334896-A1 | Substituted Heterocyclic Derivative, Preparation Method And Use Thereof | FAAH, NAAA, FAAH2 | NAAA 2/4885FAAH 1/4885BRD4 457/4885 |
| US-10174015-B2 | Substituted heterocyclic derivative, preparation method and use thereof | DHPS, CYP3A5, CYP3A4 | NAAA 557/4885FAAH 934/4885BRD4 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.