SCHEMBL94275

SCHEMBL94275

[CH2]CC(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 6/20 0.52
TAAR1 Q96RJ0 1/20 0.52
HRH1 P35367 5/20 0.48
TDP1 Q9NUW8 1/20 0.44
DPP4 P27487 2/20 0.43
F2 P00734 1/20 0.43
TSHR P16473 1/20 0.43
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
MTOR P42345 1/20 0.42
RAB9A P51151 1/20 0.42
GRM7 Q14831 1/20 0.42
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9027147 0.89 HTR2A (0.44) HTR2ATAAR1HRH1TDP1DPP4
SCHEMBL7429108 0.85 IDO1 (0.50) HTR2ATAAR1TDP1TSHRCHRNB2
SCHEMBL7430169 0.85 CYP19A1 (0.44) HTR2ATAAR1HRH1TSHRCHRNB2
SCHEMBL7411961 0.80 ACP3 (0.53) TDP1RAB9ALMNA
SCHEMBL8325499 0.80 IDO1 (0.49)
SCHEMBL8827578 0.80 CFTR (0.59) LMNA
SCHEMBL8324166 0.80 ACP3 (0.47) LMNA
SCHEMBL17351648 0.80 SLC6A2 (0.49)
SCHEMBL8322755 0.80 KIF11 (0.41) HTR2ATAAR1HRH1TDP1LMNA
SCHEMBL8321874 0.80 CPN1 (0.46) HTR2ATAAR1HRH1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2064 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987557-B2 Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof TRIOPTOTEC GMBH (DE) 2024-05-21 US claimed
CN-115279875-B Grease composition 出光兴产株式会社 2024-01-12 CN claimed
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 US claimed
WO-2023208725-A1 AMORPHOUS COPOLYCARBONATE WITH PHENOLIC BUILDING BLOCKS COVESTRO DEUTSCHLAND AG (DE) 2023-11-02 WO claimed
CN-113490734-B Grease composition 出光兴产株式会社 2023-08-01 CN claimed
CN-113490733-B Grease composition, and method and device for lubricating sliding mechanism using same 出光兴产株式会社 2023-07-28 CN claimed
CN-113508171-B Grease composition 出光兴产株式会社 2023-06-06 CN claimed
CN-113348234-B Grease composition 出光兴产株式会社 2023-03-21 CN claimed
CN-112639060-B Grease composition for constant velocity joints 出光兴产株式会社 2022-12-09 CN claimed
US-11059818-B2 Triazolopyridine inhibitors of myeloperoxidase BRISTOL-MYERS SQUIBB COMPANY (US) 2021-07-13 US claimed
US-4806534-A SMOOTH MUSCLE RELAXANT, CALCIUM ANTAGONIST RECORDATI S.A., CHEMICAL & PHARMACEUTICAL COMPANY (CH) 1989-02-21 US claimed
EP-0076755-B1 ACYLAMINO-4-AZA-1-ADAMANTANES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTIC USE ETABLISSEMENTS NATIVELLE S.A. (FR) 1988-01-13 EP claimed
CN-86107544-A The preparation method of flavone derivative 1987-11-25 CN claimed
EP-0223744-A2 Flavone derivatives RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1987-05-27 EP claimed
EP-0215297-A2 Substituted dipeptide amides G.D. Searle & Co. (US) 1987-03-25 EP claimed
US-4634716-A ANGIOTENSIN CONVERTING ENZYME INHIBITORS MERCK & CO., INC. (US) 1987-01-06 US claimed
US-4594341-A Hypotensive agent MERCK & CO., INC. (US) 1986-06-10 US claimed
US-4578382-A ANTIARRHYTHMIA AGENTS ETABLISSEMENTS NATIVELLE S.A. (FR) 1986-03-25 US claimed
EP-0156433-A2 Anti-virally active pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1985-10-02 EP claimed
EP-0027935-B1 DIELECTRIC LIQUID COMPOSITION USED IN AN ELECTRICAL CAPACITOR McGraw-Edison Company (US) 1984-07-25 EP claimed